Targeted isotretinoin in neuroblastoma: kinetics, genetics, or absorption.
Where this comes from
- Record sourced from PubMed, PMID 23209029.
- Also identified by DOI 10.1158/1078-0432.CCR-12-3313 and PMC identifier 5892183.
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Abstract
Isotretinoin (13-cis-retinoic acid; 13-cisRA) has been shown to significantly improve survival for children with high-risk neuroblastoma. Pharmacokinetics of isotretinoin may be negatively affected by the mode of drug administration and the dosing formula.
Medical subject headings
- Antineoplastic Agents
- Isotretinoin
- Neuroblastoma