Modeling transcriptome dynamics in a complex world.
basic_science · Level V
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- Record sourced from PubMed, PMID 23217702.
- Also identified by DOI 10.1016/j.cell.2012.11.031.
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Abstract
An accurate prediction of how extrinsic stimuli influence changes in gene expression has been challenging. In this issue, Nagano and colleagues successfully model genome-wide mRNA expression changes under variable environmental conditions in rice, raising hopes that scientists will soon be able to predict genome-wide transcriptional responses in a variety of organisms in uncontrolled real-world settings.