PEM anchorage on titanium using catechol grafting.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23226262.
- Also identified by DOI 10.1371/journal.pone.0050326 and PMC identifier PMC3251166.
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Abstract
BACKGROUND: This study deals with the anchorage of polyelectrolyte films onto titanium surfaces via a cathecol-based linker for biomedical applications. METHODOLOGY: The following study uses a molecule functionalized with a catechol and a carboxylic acid: 3-(3,4-dihydroxyphenyl)propanoic acid. This molecule is anchored to the TiO(2) substrate via the catechol while the carboxylic acid reacts with polymers bearing amine groups. By providing a film anchorage of chemisorption type, it makes possible to deposit polyelectrolytes on the surface of titanium. PRINCIPAL FINDINGS: Infrared spectroscopy (ATR-FTIR), X-ray photoelectron spectroscopy (XPS), contact angle and atomic force microscopy (AFM) measurements show that the different steps of grafting have been successfully performed. CONCLUSIONS: This method based on catechol anchorage of polyelectrolytes open a window towards large possibilities of clinical applications.