Slicing, stacking and rolling: fabrication of nanostructured collagen constructs from tendon sections.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23233344.
- Also identified by DOI 10.1002/adhm.201200319.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A novel method for fabricating both multilayer stacked 2D and 3D tubular constructs composed of sheets of aligned collagen fibers is described. These structures are created by decellularizing native tendon and sectioning the material into thin sheets using a cryo-microtome. This fabrication method preserves the collagens natural strength as well as the fiber structure which would aid in directing aligned cell growth.
Medical subject headings
- Collagen
- Nanostructures
- Nanotechnology
- Tendons
- Tissue Engineering
- Tissue Scaffolds