Capture and stimulated release of circulating tumor cells on polymer-grafted silicon nanostructures.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23255101.
- Also identified by DOI 10.1002/adma.201203185 and PMC identifier 3786692.
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Abstract
A platform for capture and release of circulating tumor cells is demonstrated by utilizing polymer grafted silicon nanowires. In this platform, integration of ligand-receptor recognition, nanostructure amplification, and thermal responsive polymers enables a highly efficient and selective capture of cancer cells. Subsequently, these captured cells are released upon a physical stimulation with outstanding cell viability.
Medical subject headings
- Cell Separation
- Nanowires
- Neoplastic Cells, Circulating
- Silicon