Quantitative analysis of peptides and proteins in biomedicine by targeted mass spectrometry.
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- Record sourced from PubMed, PMID 23269374.
- Also identified by DOI 10.1038/nmeth.2309 and PMC identifier 3943160.
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Abstract
Targeted mass spectrometry (MS) is becoming widely used in academia and in pharmaceutical and biotechnology industries for sensitive and quantitative detection of proteins, peptides and post-translational modifications. Here we describe the increasing importance of targeted MS technologies in clinical proteomics and the potential key roles these techniques will have in bridging biomedical discovery and clinical implementation.
Medical subject headings
- Biomarkers
- Biomedical Research
- Mass Spectrometry
- Peptide Fragments
- Proteins
- Proteome
- Proteomics