Prediction of infusion rates: computer study.
basic_science · Level V
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- Record sourced from PubMed, PMID 2328176.
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Abstract
The administration of two test doses in the ratio 1:0.5 has been shown to provide sufficient data (time intervals) to predict the infusion rate necessary to maintain the concentration of a drug at the therapeutic threshold in a two-compartment pharmacokinetic model. If the relationship between the durations of action of the test doses is linear, only one test dose may be needed to predict the infusion rate.
Medical subject headings
- Computers
- Models, Biological
- Pharmaceutical Preparations