Electrolyte-gated organic field-effect transistor sensors based on supported biotinylated phospholipid bilayer.

Magliulo, Maria; Mallardi, Antonia; Mulla, Mohammad Yusuf; Cotrone, Serafina; Pistillo, Bianca Rita; Favia, Pietro; Vikholm-Lundin, Inger; Palazzo, Gerardo et al. · Adv Mater · 2013

basic_science · Level V

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Abstract

Anchored, biotinylated phospholipids forming the capturing layers in an electrolyte-gated organic field-effect transistor (EGOFET) allow label-free electronic specific detection at a concentration level of 10 nM in a high ionic strength solution. The sensing mechanism is based on a clear capacitive effect across the PL layers involving the charges of the target molecules.

Medical subject headings