Memoirs of a reincarnated T cell.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 23290132.
- Also identified by DOI 10.1016/j.stem.2012.12.009 and PMC identifier 6352969.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
In two studies published in this issue of Cell Stem Cell,Nishimura et al. (2013) and Vizcardo et al. (2013) reprogram mature, antigen-specific cytotoxic T cells into induced pluripotent stem cells (iPSCs). The antigen-specific iPSCs can be redifferentiated into "rejuvenated" proliferative T cells and have broad applications for adoptive immunotherapy.
Medical subject headings
- Cell Culture Techniques
- Cell Differentiation
- Induced Pluripotent Stem Cells
- MART-1 Antigen
- T-Lymphocytes
- T-Lymphocytes, Cytotoxic