Spondyloarthritis in 2012: Advances in pathogenesis through animal models and imaging.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23296391.
- Also identified by DOI 10.1038/nrrheum.2012.233.
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Abstract
Advances in 2012 have helped to solve several established mysteries in spondyloarthritis (SpA) - why T-cell-directed therapies have not delivered the expected efficacy and how the IL-23-IL-17 cytokine axis is linked to the specific pathology of SpA. The opportunity to influence disease progression at inflammatory lesions using anti-TNF agents may be fleeting.
Medical subject headings
- Interleukin-23
- Signal Transduction
- Spondylarthritis