Pleurodesis outcome in malignant pleural mesothelioma.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 23299964.
- Also identified by DOI 10.1136/thoraxjnl-2012-203043.
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Abstract
Few data exist on the pleurodesis outcome in patients with malignant pleural mesothelioma (MPM). A retrospective review of the Western Australian Mesothelioma Registry over 5 years revealed 390 evaluable patients. Only a subset of patients (42.3%) underwent pleurodesis, surgically (n=78) or by bedside instillation of sclerosants (n=87). Surgical pleurodesis showed no advantages over bedside pleurodesis in efficacy (32% vs 31% failures requiring further drainage, p=0.98), patient survival (p=0.52) or total time spent in hospital from procedure till death (p=0.36). No clinical, biochemical or radiographic parameters tested adequately predict pleurodesis outcome.
Medical subject headings
- Mesothelioma
- Pleural Neoplasms
- Pleurodesis
- Talc