A historic skeleton with osteomyelosclerosis.

Kramar, C; Baud, C A; Lagier, R · Arch Pathol Lab Med · 1990

case_report · Level V

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Abstract

A case of osteomyelosclerosis (ie, an advanced stage of the myeloproliferative disorder named myelofibrosis) was reported in an adult male skeleton dating from the 17th or 18th century. The diagnosis was founded on the presence of a newly formed microspongiosa and a thickening of the preexisting trabeculae. A subperiosteal thickening of the cortical bone was also noted.

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