A splicing twist on metastasis.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23345607.
- Also identified by DOI 10.1126/scitranslmed.3005424.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
An oncogenic splice variant of the transcription factor KLF6 is associated with metastasis and poor survival in node-negative breast cancer patients and promotes the epithelial-to-mesenchymal transition by regulating Twist.
Medical subject headings
- Alternative Splicing
- Kruppel-Like Transcription Factors
- Neoplasm Metastasis