Triggering cell adhesion, migration or shape change with a dynamic surface coating.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23355329.
- Also identified by DOI 10.1002/adma.201204474.
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Abstract
There's an APP for that: cell-repellent APP (azido-[polylysine-g-PEG]) is used to create substrates for spatially controlled dynamic cell adhesion. The simple addition of a functional peptide to the culture medium rapidly triggers cell adhesion. This highly accessible yet powerful technique allows diverse applications, demonstrated through tissue motility assays, patterned coculturing and triggered cell shape change.
Medical subject headings
- Cell Movement
- Cell Shape
- Coated Materials, Biocompatible