When the drugs don't work: the potential of glutamatergic antipsychotics in schizophrenia.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 23377207.
- Also identified by DOI 10.1192/bjp.bp.112.110999.
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Abstract
Currently available antipsychotic drugs target dopaminergic neurotransmission. Many patients do not respond fully to these treatments, and there has been considerable effort to investigate alternative targets. Here we summarise the rationale and recent evidence supporting efforts to develop glutamatergic antipsychotic drugs.
Medical subject headings
- Excitatory Amino Acid Agents
- Receptors, Glutamate
- Schizophrenia