Effect of HIV on liver fibrosis among HCV-infected African Americans.

Silver, D; Karnik, G; Osinusi, A; Silk, R; Stabinski, L; Doonquah, L; Henn, S; Teferi, G et al. · Clin Infect Dis · 2013

retrospective_cohort · Level III

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Abstract

Degree of liver fibrosis largely determines treatment urgency for hepatitis C virus (HCV). This retrospective study examined fibrosis stages and predictive factors in African Americans with HCV monoinfection and human immunodeficiency virus (HIV)/HCV coinfection. Nearly 50% of patients had early-stage fibrosis in the study, despite the long duration of infection in many patients. HIV was associated with the early fibrosis group. These results indicate that a large proportion of patients with HCV infection, including those with HIV, could possibly await more-effective and better-tolerated treatment.

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