T helper 17 cells in airway diseases: from laboratory bench to bedside.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 23381314.
- Also identified by DOI 10.1378/chest.12-0598.
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Abstract
T helper 17 (Th17) cytokines are now widely believed to be critical for the regulation of various chronic immune diseases. Investigations have revealed a significant role for IL-17 cytokines in regulating inflammation and modulating lung and airway structural cells in asthma and COPD. In this review, our current understanding of the role of Th17-associated cytokines in airway diseases is summarized. Therapeutic approaches targeting IL-17 during asthma and COPD are also discussed.
Medical subject headings
- Lung Diseases
- Th17 Cells
- Translational Research, Biomedical