SWItching on epidermal cell fate.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23395438.
- Also identified by DOI 10.1016/j.stem.2013.01.011 and PMC identifier 4454396.
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Abstract
Chromatin regulatory complexes are well known regulators of stem cell fate; however, the mechanisms regulating their activity are not well understood. In this issue of Cell Stem Cell, Bao et al. (2013) show that ACTL6a inhibits targeting of the SWI/SNF complex to differentiation genes, thereby preserving the epidermal progenitor state.