Genetic loci ordering instability: an example.
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- Record sourced from PubMed, PMID 2339708.
- Also identified by PMC identifier 1683812.
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Abstract
In attempting to establish the order of genetic loci by constructing a map from pairwise linkage data, one assumes that the loci satisfy a linear-order relation. If the data utilized in the construction are not consistent with the linear-order assumption, then a very small change in the data may lead to a large qualitative change in the map. An example of such an instability is presented in this paper.
Medical subject headings
- Chromosome Mapping
- Genetic Linkage
- Models, Genetic