Power in numbers: meta-analysis to identify inhibitor-sensitive tumor genotypes.
meta_analysis · Level I
Where this comes from
- Record sourced from PubMed, PMID 23403632.
- Also identified by DOI 10.1158/1078-0432.CCR-13-0169 and PMC identifier 4327821.
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Abstract
Widespread tumor genotyping has increased the complexity of lung cancer care, often identifying mutations of uncertain clinical significance. In the accompanying article, the authors carried out a meta-analysis of the published literature on EGF receptor (EGFR) genotype and erlotinib/gefitinib sensitivity to develop a publicly accessible database to inform patient care.
Medical subject headings
- Carcinoma, Non-Small-Cell Lung
- ErbB Receptors
- Lung Neoplasms
- Mutation
- Protein Kinase Inhibitors