Nucleating new branches from old.

Zheng, Yixian; Iglesias, Pablo A · Cell · 2013

basic_science · Level V

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Abstract

Centrosome- and chromatin-based microtubule nucleation pathways have been implicated in spindle assembly. Using total internal reflection fluorescent microscopy and Xenopus egg extracts, Petry et al. demonstrate that new microtubules can also nucleate and branch out from existing ones in animal cells.