A cool way to live long.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23415218.
- Also identified by DOI 10.1016/j.cell.2013.01.050.
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Abstract
In this issue, Xiao et al. challenge the notion that cold temperatures promote longevity solely through thermodynamic effects. They show that low temperatures activate a cold-sensitive cation channel, TRPA-1, which triggers a complex signaling pathway in both neurons and nonneuronal cells to extend the lifespan of Caenorhabditis elegans.