Pathology of rodent models of intestinal cancer: progress report and recommendations.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 23415801.
- Also identified by DOI 10.1053/j.gastro.2013.01.067 and PMC identifier 3660997.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
In October 2010, a pathology review of rodent models of intestinal neoplasia was held at The Jackson Laboratory. This review complemented 2 other concurrent events: a workshop on methods of modeling colon cancer in rodents and a conference on current issues in murine and human colon cancer. We summarize the results of the pathology review and the committee's recommendations for tumor nomenclature. A virtual high-resolution image slide box of these models has been developed. This report discusses significant recent developments in rodent modeling of intestinal neoplasia, including the role of stem cells in cancer and the creation of models of metastatic intestinal cancer.
Medical subject headings
- Colorectal Neoplasms
- Guidelines as Topic
- Research Report