Discovery of novel materials with broad resistance to bacterial attachment using combinatorial polymer microarrays.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23417823.
- Also identified by DOI 10.1002/adma.201204936 and PMC identifier 3736217.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
A new class of bacteria-attachment-resistant materials is discovered using a multi-generation polymer microarray methodology that reduces bacterial attachment by up to 99.3% compared with a leading commercially available silver hydrogel anti-bacterial material. The coverage of three bacterial species, Pseudomonas aeruginosa, Staphylococcus aureus, and uropathogenic Escherichia coli is assessed.
Medical subject headings
- Bacterial Adhesion
- Drug Design
- Microarray Analysis
- Polymethacrylic Acids