Reading the tea leaves of tumor-mediated immunosuppression.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23430024.
- Also identified by DOI 10.1158/1078-0432.CCR-12-3792 and PMC identifier 3594479.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Polyphenol E, available as Polyphenon E, is a green tea extract whose activity can be benchmarked to the presence of specific catechins such as epigallocatechin 3-gallate (EGCG). Herein, Polyphenon E is shown to reverse myeloid-derived suppressor cell activity, linking the activity of a natural product extract to cell-mediated immunity.
Medical subject headings
- Immunity, Cellular
- Neoplasms
- Plant Leaves
- Polyphenols
- Tea