ROCKing pulmonary fibrosis.
Where this comes from
- Record sourced from PubMed, PMID 23434586.
- Also identified by DOI 10.1172/JCI68417 and PMC identifier 3582155.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Clinical vignette: A 76-year-old man consults you for increasing shortness of breath over the past two years and an increasing requirement for home oxygen. A video-assisted thoracoscopic lung biopsy shows findings of usual interstitial pneumonitis, and he has no identifiable cause for pulmonary fibrosis, so he is considered to have idiopathic pulmonary fibrosis (IPF). His diffusing capacity for carbon monoxide (DLCO) is 45% of predicted, and his total lung capacity is 40% of predicted. Because of his advanced age, he is not considered a candidate for lung transplantation. What treatment should you recommend?
Medical subject headings
- Mechanotransduction, Cellular
- Myofibroblasts
- Pulmonary Fibrosis