Functional living biointerphases.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23447109.
- Also identified by DOI 10.1002/adhm.201200473.
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Abstract
Lactococcus lactis is modified to express a fibronectin fragment (FNIII₇₋₁₀) as a membrane protein. This interphase, based on a living system, can be further exploited to provide spatio-temporal factors to direct cell function at the material interface. This approach establishes a new paradigm in biomaterial surface functionalization for biomedical applications.
Medical subject headings
- Fibronectins
- Lactococcus lactis