Quit stalling or you'll be silenced.

Kim Guisbert, Karen S; Sontheimer, Erik J · Cell · 2013

basic_science · Level V

Where this comes from

Abstract

The use of small RNAs to program gene regulation and genome defense necessitates ever-changing choices about the sequences used for small-RNA biogenesis. Dumesic et al. now reveal stalled spliceosomes as a trigger for small-RNA biogenesis in the pathogenic fungus Cryptococcus neoformans.