Treatment of constitutional delay of growth and puberty with oxandrolone compared with growth hormone.

Buyukgebiz, A; Hindmarsh, P C; Brook, C G · Arch Dis Child · 1990

rct · Level II

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Abstract

The effects of oxandrolone or biosynthetic human growth hormone (r-hGH) on the growth of 26 boys with constitutional delay of growth and puberty were studied. Both regimens increased growth rate twofold, oxandrolone to a greater extent than r-hGH. We conclude that oxandrolone is a more effective method of increasing growth rate in such children.

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