Glucosamine-conjugated nanoparticles for the separation of insulin-secreting beta cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23471896.
- Also identified by DOI 10.1002/adhm.201200479.
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Abstract
A small molecule, glucosamine, is used as targeting moiety for insulin-secreting beta cell separation in artificial cell mixtures and tissue samples. The specificity of glucosamine allows it to be used in cell sorting applications. In addition, a thrombin-specific cleavable peptide was used as an intermediary to release nanoparticles from cell surfaces to facilitate cell attachment and proliferation.
Medical subject headings
- Cell Separation
- Glucosamine
- Insulin-Secreting Cells
- Nanoparticles