Novel SIRT1 mutation linked to autoimmune diabetes in humans.
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- Record sourced from PubMed, PMID 23473025.
- Also identified by DOI 10.1016/j.cmet.2013.02.014 and PMC identifier 4168898.
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Abstract
Sirtuins are best known for their role in aging but also regulate many different biological processes. A study in this issue of Cell Metabolism (Biason-Lauber et al., 2013) now identifies a mutation in human SIRT1 causing a familial form of autoimmune diabetes.