A new "immunological" role for adipocytes in obesity.
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- Record sourced from PubMed, PMID 23473027.
- Also identified by DOI 10.1016/j.cmet.2013.02.015.
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Abstract
Obesity-induced insulin resistance is associated with low-grade adipose tissue inflammation, but the mechanism driving this process remains unclear. In this issue of Cell Metabolism, a study by Deng et al. (2013) demonstrates a direct immunological role of adipocytes in instigating adipose inflammation via a MHCII-dependent process.