Teaching NeuroImages: a neurosyphilis case presenting with atypical neuroradiologic findings.

Agayeva, Nergiz; Karli-Oguz, Kader; Saka, Esen · Neurology · 2013

case_report · Level V

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Abstract

A 51-year-old man presented with memory loss, behavioral changes, and generalized seizures for 4 months. Mini-Mental State Examination (MMSE) score was 11. MRI showed hyperintensities in multiple cortical areas and thalami (figure, A-C). Diffusion was restricted in certain areas (figure, D and E). Treponemal antibody tests were positive in serum and CSF. He was treated with penicillin. Six months later, his behavior and memory improved considerably (MMSE 20).

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