The effect of platelet releasate on wound healing in animal models.
basic_science · Level V
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Abstract
The alpha granules of platelets contain growth factors that are important in wound healing. We found that a major effect of thrombin-induced human platelet releasates in animal models of wound healing is to enhance the development of granulation tissue and new connective tissue matrix. These studies provide further evidence that platelet-derived protein factors may be useful in treating full-thickness dermal wounds by increasing the rate of granulation tissue formation.
Medical subject headings
- Blood Platelets
- Wound Healing