Spinning the web of cell fate.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23498930.
- Also identified by DOI 10.1016/j.cell.2013.02.052 and PMC identifier 4018449.
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Abstract
Spatiotemporal changes in nuclear lamina composition underlie cell-type-specific chromatin organization and cell fate, suggesting that the lamina forms a dynamic framework critical for genome function, cellular identity, and developmental potential.
Medical subject headings
- Cell Differentiation
- Cell Lineage
- Nuclear Lamina