Cost analysis of adjuvant therapy with XELOX or FOLFOX4 for colon cancer.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 23506229.
- Also identified by DOI 10.1111/codi.12216.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
XELOX and FOLFOX4 have both been recommended as adjuvant therapy for stage III colon cancer. This study compared the two regimens in terms of monetary costs, assuming equal efficacy of the therapies. A retrospective financial audit was conducted of the medical records of patients treated with XELOX or FOLFOX4. All itemized expenses were classified as direct (chemotherapy, hospitalization, venous access and tests), related to adverse effects due to the adjuvant therapy, or societal (travel and time costs). The cost of supportive care was not included. XELOX involved less total cost to the patient than FOLFOX4 (a difference of US$2857.68), fewer costs related to adverse effects ($668.97), and less travel ($26.07) and time ($390.93) expenditure per patient. The results indicate that, overall, XELOX is a more affordable option than FOLFOX4 in China.
Medical subject headings
- Antineoplastic Combined Chemotherapy Protocols
- Chemotherapy, Adjuvant
- Colonic Neoplasms
- Cost of Illness
- Deoxycytidine
- Fluorouracil
- Hospitalization