PHISTO: pathogen-host interaction search tool.

Durmuş Tekir, Saliha; Çakır, Tunahan; Ardiç, Emre; Sayılırbaş, Ali Semih; Konuk, Gökhan; Konuk, Mithat; Sarıyer, Hasret; Uğurlu, Azat et al. · Bioinformatics · 2013

other · Level V

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Abstract

Knowledge of pathogen-host protein interactions is required to better understand infection mechanisms. The pathogen-host interaction search tool (PHISTO) is a web-accessible platform that provides relevant information about pathogen-host interactions (PHIs). It enables access to the most up-to-date PHI data for all pathogen types for which experimentally verified protein interactions with human are available. The platform also offers integrated tools for visualization of PHI networks, graph-theoretical analysis of targeted human proteins, BLAST search and text mining for detecting missing experimental methods. PHISTO will facilitate PHI studies that provide potential therapeutic targets for infectious diseases. http://www.phisto.org. saliha.durmus@boun.edu.tr Supplementary data are available at Bioinformatics online.

Medical subject headings