Rapid, guanosine 5'-diphosphate-induced, gelation of chitosan sponges as novel injectable scaffolds for soft tissue engineering and drug delivery applications.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23554366.
- Also identified by DOI 10.1002/adhm.201200371.
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Abstract
Novel injectable chitosan sponges based on rapid ionic crosslinking using guanosine 5'-diphosphate are introduced. The rapid gelation, high water retention, desirable physicochemical properties, soft tissue-like mechanical properties, and excellent cytocompatibility make these injectable sponges promising candidates for tissue regeneration and drug delivery applications.
Medical subject headings
- Chitosan
- Drug Carriers
- Gels
- Guanosine Diphosphate
- Tissue Engineering