This niche is a maze; an amazing niche.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 23561440.
- Also identified by DOI 10.1016/j.stem.2013.03.012 and PMC identifier 3964479.
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Abstract
The cellular identity of niche cells that regulate hematopoietic stem cell (HSC) self-renewal and differentiation has been debated for several years. Two recent studies in Nature (Ding and Morrison, 2013; Greenbaum et al., 2013) have shed light into the bone marrow stromal subsets making CXCL12, a chemokine critical for HSC maintenance.