How is the hungry brain like a sieve?

Myers, Martin G · Cell Metab · 2013

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Abstract

Whether some hypothalamic neurons have direct access to circulating metabolic cues represents a crucial question that has been intensely debated. New findings reveal that fasting promotes "leakiness" of some hypothalamic blood vessels, increasing the access of circulating factors to certain hypothalamic neurons that control feeding (Langlet et al., 2013).