Raggin' on T-bet.

Locksley, Richard M · Cell Metab · 2013

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Abstract

Although increasing adiposity is usually associated with adipose tissue infiltration by inflammatory cells and systemic insulin resistance, Stolarczyk et al. (2013) report in this issue that mice deficient in the T-box transcription factor, T-bet, display a dissociated phenotype with enhanced perigonadal adipose but enhanced insulin sensitivity.