pH-controlled delivery of nanoparticles into tumor cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23564477.
- Also identified by DOI 10.1002/adhm.201300013.
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Abstract
Nanoparticles target tumor cells by pH-controlled means. Nanoparticles carry three synergistic delivery functions: 1) tumor tissue targeting by the EPR effect; 2) tumor cell targeting by pHLIP-mediated membrane-localization; and 3) tumor cell uptake by adsorptive-mediated endocytosis.
Medical subject headings
- Drug Delivery Systems
- Nanoparticles
- Neoplasms