Defined polymer-peptide conjugates to form cell-instructive starPEG-heparin matrices in situ.

Tsurkan, Mikhail V; Chwalek, Karolina; Prokoph, Silvana; Zieris, Andrea; Levental, Kandice R; Freudenberg, Uwe; Werner, Carsten · Adv Mater · 2013

basic_science · Level V

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Abstract

Poly(ethylene glycol)-peptide- and glycosaminoglycan-peptide conjugates obtained by a regio-selective amino acid protection strategy are converted into cell-instructive hydrogel matrices capable of inducing morphogenesis in embedded human vascular endothelial cells and dorsal root ganglia.

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