Synthesis of protein-based, rod-shaped particles from spherical templates using layer-by-layer assembly.

Zhou, Zhimin; Anselmo, Aaron C; Mitragotri, Samir · Adv Mater · 2013

basic_science · Level V

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Abstract

Nanorods provide distinct advantages over their spherical counterparts for targeted drug delivery. Here, a novel method is described for the synthesis of biocompatible protein nanorods from spherical polystyrene templates using the layer-by-layer (LBL) technique. These nanorods can be used as a vehicle for the delivery of therapeutic agents to diseased sites.

Medical subject headings