Xpert MTB/RIF testing of stool samples for the diagnosis of pulmonary tuberculosis in children.

Nicol, Mark P; Spiers, Karalene; Workman, Lesley; Isaacs, Washiefa; Munro, Jacinta; Black, Faye; Zemanay, Widaad; Zar, Heather J · Clin Infect Dis · 2013

cross_sectional · Level IV

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Abstract

In a pilot accuracy study, stool Xpert testing from 115 children with suspected pulmonary tuberculosis (PTB) detected 8/17 (47%) culture-confirmed tuberculosis cases, including 4/5 (80%) HIV-infected and 4/12 (33%) HIV-uninfected children. Sputum Xpert detected 11/17 (65%) cases. Stool holds promise for PTB diagnosis in HIV-infected children.

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