Beyond the sympathetic tone: the new brown fat activators.

Villarroya, Francesc; Vidal-Puig, Antonio · Cell Metab · 2013

review · Level V

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Abstract

If we could avoid the side effects associated with global sympathetic activation, activating brown adipose tissue to increase thermogenesis would be a safe way to lose weight. The discovery of adrenergic-independent brown fat activators opens the prospect of developing this alternative way to efficiently and safely induce negative energy balance.

Medical subject headings