Combined effect of mussel-inspired surface modification and topographical cues on the behavior of skeletal myoblasts.

Ku, Sook Hee; Park, Chan Beum · Adv Healthc Mater · 2013

basic_science · Level V

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Abstract

The combined effect of mussel-inspired polydopamine (PDA) surface functionalization and topographical cues on the behavior of skeletal myoblasts is described. On PDA-modified nanofibers, myogenic protein expression and the fusion of myoblasts are increased significantly compared with those on unmodified nanofibers. The multinucleate myotubes on the aligned nanofibers are oriented in a direction parallel to the nanofibers.

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