Diamond-lipid hybrids enhance chemotherapeutic tolerance and mediate tumor regression.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23584895.
- Also identified by DOI 10.1002/adma.201300343 and PMC identifier 3872062.
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Abstract
Self-assembled nanodiamond-lipid hybrid particles (NDLPs) harness the potent interaction between the nanodiamond (ND)-surface and small molecules, while providing a mechanism for cell-targeted imaging and therapy of triple negative breast cancers. Epidermal growth factor receptor-targeted NDLPs are highly biocompatible particles that provide cell-specific imaging, promote tumor retention of ND-complexes, prevent epirubicin toxicities and mediate regression of triple negative breast cancers.
Medical subject headings
- Antineoplastic Agents
- Breast Neoplasms
- Drug Tolerance
- Lipids
- Nanodiamonds