Clinical uncertainties, health service challenges, and ethical complexities of HIV "test-and-treat": a systematic review.
systematic_review · Level I
Where this comes from
- Record sourced from PubMed, PMID 23597344.
- Also identified by DOI 10.2105/AJPH.2013.301273 and PMC identifier 3670656.
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Abstract
Despite the HIV "test-and-treat" strategy's promise, questions about its clinical rationale, operational feasibility, and ethical appropriateness have led to vigorous debate in the global HIV community. We performed a systematic review of the literature published between January 2009 and May 2012 using PubMed, SCOPUS, Global Health, Web of Science, BIOSIS, Cochrane CENTRAL, EBSCO Africa-Wide Information, and EBSCO CINAHL Plus databases to summarize clinical uncertainties, health service challenges, and ethical complexities that may affect the test-and-treat strategy's success. A thoughtful approach to research and implementation to address clinical and health service questions and meaningful community engagement regarding ethical complexities may bring us closer to safe, feasible, and effective test-and-treat implementation.
Medical subject headings
- HIV
- HIV Infections
- Health Promotion