INstruct: a database of high-quality 3D structurally resolved protein interactome networks.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23599502.
- Also identified by DOI 10.1093/bioinformatics/btt181 and PMC identifier 3673217.
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Abstract
INstruct is a database of high-quality, 3D, structurally resolved protein interactome networks in human and six model organisms. INstruct combines the scale of available high-quality binary protein interaction data with the specificity of atomic-resolution structural information derived from co-crystal evidence using a tested interaction interface inference method. Its web interface is designed to allow for flexible search based on standard and organism-specific protein and gene-naming conventions, visualization of protein architecture highlighting interaction interfaces and viewing and downloading custom 3D structurally resolved interactome datasets. INstruct is freely available on the web at http://instruct.yulab.org with all major browsers supported.
Medical subject headings
- Databases, Protein
- Protein Interaction Domains and Motifs
- Protein Interaction Mapping